Urosolvine Effervescent Granules For management

of urolithiasis and gouty arthritis

Composition: £ad. 5 I (sachct) contains: Ingrtdlt.nts: Piperazine Olnlt (Eq. To O.IlSa.Plperazine Cokhldnt CI")'Itlll AtropineSulpblte Inactive Ingredients: Acth"!

Sod.Bicarboaalt

0.1408 & H)dntt) • .3 mc '.128 mc

,Clint .dd anb) •• Tartaric

Pbarmaceutical form: [ffrneKeD' Pbarmac:otberapeutic

group:

~Ktioo:

Kid,

P.V.P, Lemo •

.n. Seerese.

Gnnule

L'rkosurk

.,..t--..

-u~. ec:ntn ••• retIlIIel' •••••••••• raft.. • PiprraziH bolt __ (or .'D~ )"ftn te be •• acme tilt trtatmtat.rput lacrnst tlllt sol.billt}' .rantts" the:.rt.~ Ills rdad\'fly ItOO-tosk. • CokhkiM g,hn npid rtlitfrrom l"Iia u. acute attacks .rCOwt and tilled".. tbat it eu be • .sed as •• diagnostic Iitat ia loat .Dd pelt! artbritis. CokbidM Alth.ugh it is IIIlebl)' rfJ«tJ't in trutillg acule goaty arUritis, it is lot dftttht

dr.c"

and

unnar) litbiasis.lt

is

claimed 10

is sp«iflc for tItiJ condition to ttlt-nltne pos: ItS uti-infbmmatory properdts.. (orOlhntypn of pais. It is nOI u a.algtsk ud don: not .rrtct .rie acklclnnlltt. IIISttSd.,.(okbklll~bl.dJ to prolrilliin mkrotubuln o( DeutropbllJ. Tills blnding,ln turn, Inhibits tbe mlcnrioD o(otutropllllls iDtoUtearea o(lan.mmaUon, teereby loterferinl wUh tbe lanammatol') mpollse 10 arete cr)ltal deposltion.AtI'9piM:sulphate ls added to refteve tbe spum o(the uri.ary treet,

Pharmacokinetics: - Urosoh'lne tonlal. a typka' urkosurlt agent thai pro•• ta the urinary utrellon of urlt add and tb~rtby lower Krum urk add eeeceerratlce - SodJumtlt,..te II an alkallnislng alenlSlott the alnle is to."erttd 1010 ble.rbonalt. aluliae Urillt is ddinlcdy more suitable for the tltretlon of untts In a mort soluble fora.

Indicltions: -Atutt alld tbroak lout -Gouty artllntit -Fer prwpllJb

Dosa aod d .

IItJU:nb (

.riaaJ')

anle stonts).

Intioo:

_n

- •• Kilit atUCk. _s:adwt distolnd ill a hal(glass er water 6 lima dally. - To prn-eatamte __ k: 2 utbets diuolnd In a glass o(wattr 1 dally. -As a prop.) : 2 SKkIJ dlnohtd in a glass er weter ence daJl).

Conrra indicatioo.J: to "r of the compolltDtsof the dna.

-Kaow ••• ~~.

·BIood dyxnoIoI or lI)perbiemla

-, eete ddI)~""

Side etrfC'b: 0rcaIIM.aII" •••••• Drug iJI!enClio

"omJdll&.abdomlna'pain a.d diarrbta may eeeer,

:

....•...

P.-.puc) ucllactatioo:

-~ - II •••••••.•

11

~.

nrzapptan

I.

brutt milk.

PrKIatioD Ind wlraings:

crr. reeel

- Lseci widt aatioal. patitaUi 'fitllseriow - lt should Ilot be: uK'd III thildren • etnatria.,

Packace

, hepatit, aad ttlrdiovUC'lllardlMrd~ debililated patients alldllunllll women,.

...=:-~-:=:'_ =~..:-.

aDd storage:

·C.". •••• Io(ll.5adlmXSC....y.er1n.fkt. • tart.t t.e.penhtrt ••• utftd.ia& 25 -C

JIlStnICIio •• to palko -R.nt.n /I

i. a dry platt.

, ••.AlrTka~

'''nal ctartd b .The l.L[. C•• for Pharmaceuticals and ChemluJ lod. tri • Cairo· A.R.E. R.c.c. JJ5668

~.::...--==.=

===--===-. j":-

i

I 1 212811 Cod~

451106

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