MFN-002 MASTER OF SCIENCE (DIETETICS AND FOOD SERVICE MANAGEMENT) Term-End Examination
r)
December, 2009
1-r)
o MFN-002 : NUTRITIONAL BIOCHEMISTRY Time : 2 1 hours
Maximum Marks : 75
Note : Answer four questions in all. Question No. 1 is
compulsory. 1.
(a) Explain briefly the following statements :
8
Arachidonic acid is classified as an w6 fatty acid. Receptors for Group I hormones are located inside the cell. Competitive inhibitor raises the apparent km of the enzyme. Folic acid functions in one - carbon metabolism. With the help of chemical structures give the reaction which forms the following compounds : (i)
Citrulline (ii) 3-keto acyl CoA
What do you understand by the term 'Gene Hunt' ? MFN-002
5
1
2
P.T.O.
(a)
Explain the effect of substrate concentration, temperature and pH on the reaction velocity of enzyme catalysed reactions.
12
(b)
Discuss the regulation of glycogenesis and glycogenolysis.
8
(a)
Explain how the presence of the following enzymes helps metabolism :
12
Cytochrome oxidase Glyceraldehyde-3-P dehydrogenase Acetyl CoA carboxylase Glutamine synthetase
4.
(b)
What are the functions of zinc in normal maintenance of human health ?
8
(a)
Discuss the digestion and absorption of dietary proteins.
8
(b)
Explain how the absence of the following enzymes impairs metabolism : Fructose-1, 6-bisphosphatase Fumaryl acetoacetate hydrolase Carbamoyl phosphate synthetase I Histidase
MFN-002
2
12
(a) Give the steps involved in the oxidation of a molecule of acetyl-CoA in the citric acid cycle.
15
(b) Discuss the metabolism of very low density lipoproteins ? (VLDL).
5
(a) Differentiate between : (i) i)
8
Glucogenic and ketogenic amino acids Hereditary fructose intolerance and lactose intolerance Palmitic acid and linoleic acid Epimers and anomers
(b) Discuss the regulation of the following : cholesterol biosynthesis glycolysis (iii) MFN-002
pyruvate dehydrogenase complex 3
12
7.
Write short notes on any four of the following : 4x5=20 Glycogen storage diseases Mechanism of action of group II hormones Vitamin K functions Nucleic acids - classification and structure (e)
1. (a) Explain briefly the following statements : 8. Arachidonic acid is classified as an. w6 fatty acid. Receptors for Group I hormones are. located inside the cell.
18. Discuss the biological role of the following trace elements. i) Copper. ii) Chromium. iii) Manganese. 19. What is human genome project ? Discuss the concept ...
β-oxidation. 11. What is replication ? Explain the process of DNA replication. 12. What are enzymes ? How are they classified ? Give their characteristics. P.T.O..
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