Modifications in the Theory of Epidemiological Transition

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Modifications in the Theory of Epidemiological Transition

Omran proposed a three-stage theory of epidemiologic transition (1971), which is an attempt to account for the extraordinary advances in health care made in industrialized countries since the 18th century. The life expectancies were generally converging towards a maximum age, the most advanced countries seeming very close to it. According to the United Nations World Population Prospects, the point of convergence was 75 years (United Nations, 1975). The "cardiovascular revolution" of the 1970s launched a new period of progress. It was noticed that unexpected fall in death from man-made diseases, particularly cardio vascular diseases was happening in some Western countries, which was later described as “Stage IV transition”. Jay Olshansky and Brian Ault (1986), followed by Richard Rogers and Robert Hackenberg (1987), without criticizing the basic premises of the theory of epidemiologic transition, introduced the idea of a "fourth stage" during which the maximum point of convergence of life expectancies would seem to increase. This stage is described by Olshansky and Ault (1986) as the “age of delayed degenerative diseases” and by Rogers and Hackenberg (1987) as the “hybristic stage”. Olshansky and Ault described the following characteristics of 4th stage a. Rapidly declining death rates that are concentrated mostly at advanced ages (nearly the same pace for males and females) b. Age pattern of mortality remains almost the same as the third stage but the age distribution is shifted progressively towards older age “Unexpected shift in the age pattern of mortality by the degenerative causes for the population in advanced ages”: The major degenerative causes of death, like the 3rd stage, remain as major killer, but the risks of dying from these diseases are distributed to older ages. The source of change being attributed to a combination of factors including shift in the age structure toward older ages,advances in medical technology, health care programs for the elderly and reductions in risk factors at the population level. Jay Olshansky et al. (1990) set this new maximum at 85 years, the same as that chosen by the United Nations at the end of the 1980s for all countries (United Nations, 1989).

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Modifications in the Theory of Epidemiological Transition

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A different proposition of the 4th stage was given by Rogers and Hackenberg (1987) as the “hybristic stage”. They basically focused on different subheadings of Omran’s hypothesis such as mortality differentials among population subgroups (eg. transition favors females over males, the young over the old and whites over non-whites (In US)). They disagreed with Olshansky and Ault in source of the change. They argued increasing influence of individual behaviours and new lifestyles on mortality. The examples of these destructive lifestyle practices include sexual orientations and social pathologies like accidents, homicides, excessive drinking and smoking, and even AIDS (though it’s an infectious disease). The root cause of these destructive lifestyle practices is “hybris” - an excessive self-confidence (a belief that one can’t suffer and that one is invincible). Both of these theories, however, are not exclusive of each other. They conclude that there’s interplay between the age-cause patterns of mortality, micro level determinants such as individual behavior and social lifestyles, and macro level determinants such as health care and health promotion programs. Somewhat later, the tireless Olshansky and his colleagues took account of these developments by adding a fifth stage — that of emerging infectious diseases—to their version of the transition. Omran, in 1998,also recognized the existence of one and possibly 2 additional stages to his initial theory. He supported “the fourth stage” characterized by an ongoing rise in life-expectancy until it rises to 80-85 years; followed by a stabilization, followed by a decrease of CV diseases as a source of death; as well as by the emergence of new diseases (HIV, Hepatitis B and C, Ebola, Lyme disease) and by the revival of former diseases (cholera, malaria, dengue, tuberculosis, Chagas disease). He also added a fifth “futuristic” stage named as “the age of aspired quality of life, with paradoxical longevity and (futuristic stage) persistent inequities”. Summarizing, Epidemiologic transition (ET): Past, Present and future

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Modifications in the Theory of Epidemiological Transition

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Historical ETs

Reverse ETs

rise of infectious disease (~8000 B.C) decline of infectious disease & rise of CVD (19th-20th C) decline of cardiovascular disease (late 20th C)

rise of violence (late 20th C) resurgent infectious disease (late 20th C)

Possible future ETs Decline of cancer, dementia, etc. (21st C?)

(WHO 2000)

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